Selected Publications


Salei N, Ji X, Pakalniškytė D, Kuentzel V, Rambichler S, Li N, Moser M, Steiger K, Buch T, Anders HJ, Schraml BU. (2021) Selective depletion of a CD64 expressing phagocyte subset mediates protection against toxic kidney injury and failure. Proceedings of the National Academy of Sciences. 18(39):e2022311118.9).


Li N, Steiger S, Fei L, Li C, Shi C, Salei N, Schraml BU, Zheng Z, Anders HJ, Lichtnekert J. (2021) IRF8-Dependent Type I Conventional Dendritic Cells (cDC1s) Control post-ischemic inflammation and mildly protect against post-ischemic acute kidney injury and disease. Frontiers in Immunology. 12(2259).


Chen C, Holtkamp S, Weber J, Ince L, de Juan A, Wang C, Lutes L, Barnoud C, Kizil B, Hergenhan S, Salvermoser J, Lasch M, Deindl E, Schraml B, Baumjohann D, Scheiermann C. 2021 Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-γ. Journal of Experimental Medicine.  Aug 2;218(8):e20202377. Epub 2021 Jun 4.


Papaioannou NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU. 2021. Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice. Nature Communications, 21 (464).



Salei N*, Rambichler S*, Salvermoser J, Papaioannou NE, Schuchert R, Pakalniškytė D,  Li N,  Marschner JA,  Lichtnekert J, Stremmel C, Cernilogar F, Salvermoser M, Walzog B, Straub T, Schotta G, Anders HJ, Schulz C,  Schraml BU. 2020 The kidney contains ontogenetically distinct dendritic cell and macrophage subtypes throughout development that differ in their inflammatory properties. Journal of the American Society of Nephrology 2020, 31(2), 257-78.


*contributed equally



Papaioannou NE, Pasztoi M, Schraml BU. Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness? Front Immunol. 2019 Jan 10;9:3123. doi: 10.3389/fimmu.2018.03123. eCollection 2018. Review.



Salvermoser J, van Blijswijk J, Papaioannou NE, Rambichler S, Pasztoi M, Pakalniškytė D, Rogers NC, Keppler SJ, Straub T, Reis e Sousa C, Schraml BU. 2018. Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo. Front Immunol 9, 563–15. doi:10.3389/fimmu.2018.00699



Pakalniškytė D, Schraml BU. Tissue-Specific Diversity and Functions of Conventional Dendritic Cells. In: Vol 134. Advances in Immunology. Elsevier; 2017:89-135.


Poltorak MP, Schraml BU. 2015. Fate mapping of dendritic cells. Front Immunol. May 4;6:199.


Böttcher JP, Zelenay S, Rogers NC, Helft J, Schraml BU and Reis e Sousa C. 2015. Oncogenic transformation of dendritic cells and their precursors leads to rapid cancer development in mice. J Immunol. 195(10):5066-76.


Helft J, Böttcher J, Chakravarty P, Zelenay S, Huotari J, Schraml BU, Goubau D, Reis E Sousa C. 2015. GM-Csf mouse bone marrow cultures comprise a heterogeneous population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells. Immunity 16;42(6):1197-211.



Schraml BU, Reis e Sousa C. 2015. Defining Dendritic Cells. Current Opinion in Immunology. ePub Dec 2014.


Guilliams M, Ginhoux F, Jakubzick C, Naik SH, Onai N, Schraml BU, Segura E, Tussiwand R, and Yona S. 2014. Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat.Rev.Imm. Aug;14(8):571-8.


van Blijswijk J, Schraml BU, Rogers NC, Whitney PG, Zelenay S, Acton SE, Reis e Sousa C. 2014. Altered Lymph Node Composition in Diphtheria Toxin Receptor-Based Mouse Models to ablate Dendritic Cells. J Immunol. 94 (1), 307-315.


Whitney PG, Bär E, Osorio F, Rogers NC, Schraml BU, Deddouche S, LeibundGut-Landmann S, Reis E Sousa C. 2014. Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection. PLoS Pathog. Jul 17;10(7):e1004276.



Schraml BU, van Blijswijk J, Zelenay S, Whitney PG, Filby A, Acton SE, Rogers NC, Moncaut N, Carvajal JJ, Reis e Sousa C. 2013. Genetic tracing via expression history of DNGR-1 defines dendritic cells as a hematopoietic lineage. Cell, 154(4):843-858.



Zelenay S, Keller AM, Whitney PG, Schraml BU, Deddouche S, Rogers NC, Schulz O, Sancho D, Reis e Sousa C. 2012. The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J Clin Invest. 1;122(5):1615-27.


Poulin LF, Reyal Y, Uronen-Hansson H, Schraml BU, Sancho D, Murphy KM, Håkansson UK, Moita LF, Agace WW, Bonnet D, Reis e Sousa C. 2012. DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues. Blood; Jun 21;119(25):6052-62.



Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM. 2011. The transcription factor BATF controls the global regulators of class-switch recombination in both B and T cells. Nat Immunol. Jun;12(6):536-43.


2009 and Earlier

Schraml BU, Hildner K, Ise W, Lee WL, Smith WA, Solomon B, Sahota G, Sim J, Mukasa R, Cemerski S, Hatton RD, Stormo GD, Weaver CT, Russell JH, Murphy TL, Murphy KM. 2009. Batf expands AP-1 target specificity to control TH17 differentiation. Nature. Jul 16;460(7253):405-9.


Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, Calderon B, Schraml BU, Unanue ER, Diamond MS, Schreiber RD, Murphy TL, Murphy KM. 2008. BATF3 deficiency reveals a critical role for CD8+ dendritic cells in cytotoxic T cell immunity. Science. Nov 14;322(5904):1097-100.


Liszewski MK, Leung MK, Schraml B, Goodship TH, Atkinson JP. 2007. Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome. Mol. Immunol. Mar;44(7):1559-68.


Schraml B, Baker MA, Reilly BD. 2006. A complement receptor for opsonized immune complexes on erythrocytes from Oncorhynchus mykiss but not Ictalarus punctatus. Mol. Immunol. Apr; 43(10): 1595-603.